The following historic locations are located in Sikeston, Missouri. Please select a historic place in Sikeston to view detailed information including address information, historical signifiance, and much more.

Marshall Hotel 103 E. Malone Ave. Sikeston, MO Hotel, Specialty Store	Sikeston Fortified Village Archeological Site Address Restricted Sikeston, MO Village Site, Ceremonial Site, Graves/Burials
Sikeston St. Louis, Iron Mountain and Southern Railway Depot Front St., bet. Scott and New Madrid Sts. Sikeston, MO Rail-Related

 
 
Missouri Historic Places